Vancin-S/Vancin-S 125 mg Dosage/Direction for Use

Vancin-S 125 mg: For oral use. The capsule should not be open and should be taken with plenty of water.
Adults: The recommended Vancomycin dose for the treatment of antibiotic-associated pseudomembranous colitis caused by C. difficile and staphylococcal enterocolitis, the usual oral dosage is 500 mg to 2 g daily given in 3 or 4 divided doses for 7 to 10 days.
Pediatric: For the treatment of antibiotic-associated pseudomembranous colitis caused by C. difficile and staphylococcal enterocolitis in children, the usual oral dosage of Vancomycin is 40 mg/kg daily given in 3 or 4 divided doses for 7-10 days. Dosage of oral Vancomycin in children should not exceed 2 g daily.
Vancomycin capsules are not appropriate for the treatment of children under the age of 12 years or for adolescents unable to swallow them. Below 12 years, age-appropriate formulation should be used.
Dosage in renal impairment: Due to the very low systemic absorption, dose adjustment is unlikely, unless substantial oral absorption may occur in case of inflammatory intestinal disorders or C. difficile-induced pseudomembranous colitis. Monitoring of serum Vancomycin concentrations of patients with inflammatory intestinal disorders should be performed.
Dosage in elderly: Elderly patients are at greater risk for nephrotoxicity during or after oral therapy, monitoring recommended with oral therapy.
Vancin-S: Severe infection caused by Staphylococcus species including methicillin-resistant Staphylococcus aureus and other vancomycin-susceptible organism: Adult: 500 mg every 6 hours or 1 g every 12 hours over IV for 60 minutes.
Children: 10 mg/kg every 6 hours or 20 mg/kg every 12 hours over 60 minutes.
Neonate/infant: Initially 15 mg/kg, followed by 10 mg/kg every 12 hours & every 12 hours for infant 1 week to 1 month.
Infection in neutropenic patients: 20 mg/kg every 8 hours.